Ketamine treatment
Ketamine has been studied for treatment-resistant depression. A 2023 randomized trial compared IV ketamine with ECT in adults with nonpsychotic treatment-resistant major depression; its findings do not apply automatically to psychotic depression, every patient or every route. FDA-approved Spravato is esketamine, a different medication and administration program.
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Prince George's County · Maryland
No clinic is currently listed inside Upper Marlboro. The closest listed option is 17 straight-line miles away, in Annapolis.
Independent directory · confirm services and addresses directly. Educational information, not medical advice.
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Upper Marlboro serves as the county seat of Prince George's County, situated in central Maryland. Known for its historical roots and position within the broader Washington metropolitan area, the town provides access to various medical and mental health services. Residents exploring mental health treatments, including therapies for treatment-resistant depression, often utilize regional healthcare networks extending across central and southern Maryland. The area is defined by its mix of historic downtown elements, suburban neighborhoods, and rural surroundings, making regional travel a common aspect of specialized healthcare planning.
While our directory does not list clinics physically located within Upper Marlboro, patients can explore facilities in surrounding communities and neighboring counties. For instance, The Mood Center maintains an office in nearby Annapolis, offering IV and IM ketamine therapies alongside Spravato (esketamine). Additionally, Lumin Health Bethesda | Ketamine & Spravato Therapy provides Esketamine (Spravato) and ketamine therapy in Bethesda. Also in Bethesda, Avesta Ketamine and Wellness Bethesda lists IV ketamine therapy, Spravato (esketamine), and ketamine-assisted psychotherapy.
When considering specialized psychiatric treatments, residents of Upper Marlboro may also evaluate options in nearby municipalities. You can find more information about surrounding communities by reading our town guides for Bowie, Clinton, and Annapolis. Expanding your search across central Maryland can help you find a clinical setting that matches your specific mental health needs. Always verify services directly with the provider before scheduling an assessment.
Treatment schedules vary by clinic and treatment type, so plan transportation for each visit. Distances below are straight-line miles from Upper Marlboro.
17 miles away · Annapolis
927 West Street, 200, Annapolis
5.0(1 Google reviews)
Adler Ketamine is listed in Annapolis, Maryland. The listed appointment address is 927 West St 200, Annapolis, MD 21401, USA. Confirm the current location with the practice before travelling.
17 miles away · Annapolis
17.1 miles away · Laurel
9811 Mallard Drive, 210, Laurel
4.9(131 Google reviews)
Maryland Spravato & TMS Center lists Spravato on its official website. This office is listed in Laurel, Maryland.
18 miles away · Takoma Park
6930 Carroll Avenue, 1050, Takoma Park
5.0(8 Google reviews)
Sanctuary Holistic Therapy is listed in Takoma Park, Maryland. The listed appointment address is 6930 Carroll Ave 1050, Takoma Park, MD 20912, USA. Confirm the current location with the practice before travelling.
20.9 miles away · Laurel
585 Main Street, 145, Laurel
5.0(8 Google reviews)
Ketamine Health & Restoration is listed in Laurel, Maryland. The listed appointment address is 585 Main St 145, Laurel, MD 20707, USA. Confirm the current location with the practice before travelling.
21.6 miles away · Bethesda
4300 Montgomery Avenue, 302, Bethesda
5.0(17 Google reviews)
Calliope Health lists IV ketamine, Spravato, ketamine-assisted psychotherapy on its official website. This office is listed in Bethesda, Maryland.
When researching ketamine therapy near Upper Marlboro, patients will encounter off-label formulations, such as IV infusions, IM injections, or sublingual options. Because these treatments are not FDA-approved for psychiatric conditions, they are typically not covered by health insurance. Consequently, patients generally need to self-pay for these services. Clinics should provide a written estimate of costs before treatment begins. You should also account for travel expenses and potential lodging costs, as these protocols require repeated clinic visits over several weeks. It is important to be aware of the potential risks associated with compounded ketamine products, as highlighted by the FDA.
Alternatively, Spravato (esketamine) is an FDA-approved nasal spray for specific adult depression indications, such as treatment-resistant depression. Because it holds FDA approval, Spravato may be covered by some insurance plans. However, coverage varies significantly and often requires prior authorization from your insurer. This process usually involves demonstrating that you have tried other standard antidepressant medications without success. Out-of-pocket expenses such as copayments and deductibles will still apply. Patients should consult closely with both their insurance provider and the local clinic's billing department to understand their specific financial responsibilities before starting a Spravato protocol.
Accessing ketamine therapies or Spravato requires strict adherence to safety protocols. Spravato must be administered in a certified healthcare setting where the patient undergoes at least two hours of clinical observation. Patients are prohibited from driving until the next day after a restful sleep, necessitating a responsible adult to provide transportation. Spravato is never administered at home. While some clinicians may prescribe compounded ketamine for home use off-label, these formulations lack FDA approval for psychiatric care. The FDA explicitly warns about the risks of using these products without on-site clinical monitoring.
For residents of Upper Marlboro, frequent travel is a core requirement for both Spravato and off-label ketamine protocols. Environmental factors such as winter snow and ice, severe storms, and regional Marylandpolis traffic can impact travel times across central Maryland. Planning reliable transportation for all appointments is essential. Telehealth services may be used to support initial psychiatric assessments and follow-up consultations; however, they do not establish availability for home treatment. If you or someone you know is experiencing a mental health emergency, call 911 or contact the 988 Suicide & Crisis Lifeline by calling or texting 988 for immediate, 24/7 support.
Spravato (esketamine) is the only FDA-approved ketamine-derived treatment for specific adult depression indications, including treatment-resistant depression. It is administered as a nasal spray in a certified clinic. Off-label ketamine treatments, such as IV or IM therapies, are not FDA-approved for psychiatric conditions but are offered by some regional clinics.
No, you cannot drive yourself home after receiving Spravato or any ketamine-based therapy. Strict safety protocols mandate that patients refrain from driving or operating heavy machinery until the day following treatment, after they have had a restful sleep. A responsible adult must drive you home from the clinic.
IV ketamine therapy is prescribed off-label for psychiatric conditions and is not approved by the FDA for this purpose. Consequently, it is generally not covered by medical insurance plans. Patients typically must self-pay for these treatments. You should request a detailed written estimate from the provider beforehand.
While some specialized clinics allow you to contact them directly for an assessment, many insurance providers require a referral or documented prior authorization before covering Spravato. You will typically need to demonstrate that standard antidepressant medications have been ineffective before starting this FDA-approved nasal spray treatment.
Telehealth can often be used for initial psychiatric evaluations, treatment planning, and integration sessions with your provider. However, the actual administration of Spravato or in-clinic ketamine treatments must occur in person under direct clinical supervision. Telehealth does not permit the home administration of these controlled substances.
A typical Spravato appointment lasts slightly more than two hours. The medication administration itself is relatively brief, but patients are required by FDA guidelines to remain in the certified clinic for at least two hours of continuous observation to monitor for potential side effects before being discharged.
Costs, coverage & aftercare
IV, IM and compounded ketamine for psychiatric conditions are off-label; many programs are self-pay. Ask about assessment, medication, administration, monitoring, therapy and maintenance charges separately. We do not assume a statewide price.
Spravato is FDA-approved esketamine, not the same as ketamine infusions. Coverage is not guaranteed. Check eligibility, prior authorization, network status, drug and visit charges, deductibles and copays with your insurer and clinic.
Spravato requires a certified healthcare setting and monitoring for at least two hours. Arrange transport home; do not drive until the next day after restful sleep. For other ketamine treatments, follow your clinician's instructions. Follow-up and maintenance depend on response and tolerability.
Ask who manages your medications, how your usual clinician will receive updates, and whom to contact between visits. Neither a shortage designation nor local depression statistics show that ketamine is appropriate or effective for you. Consult a licensed physician.
Use these questions when you call or book a consultation with any Upper Marlboro provider.
Ask whether a physician, psychiatrist or anesthesiologist oversees each session and who you can reach afterward.
A good clinic reviews your history, medications, blood pressure and past treatments before recommending ketamine.
Look for continuous vital-sign monitoring and a calm, private recovery space.
IV infusions, Spravato® nasal spray, IM or sublingual options suit different goals and budgets.
Ask how the clinic coordinates with your therapist or offers integration support between sessions.
Request a written estimate for the first series and any maintenance sessions before you start.
| Clinic | Google rating | Reviews | Phone |
|---|---|---|---|
| MindBodyPinnacle Health - Mental Health Care / Spravato / TMS /Medication Management/Weight Loss and Peptides.Laurel | 4.9 | 131 | (443) 713-8643 |
| The Mood CenterAnnapolis | 4.6 | 61 | (443) 342-3611 |
| Calliope Health KetamineBethesda | 5 | 17 | (301) 828-9513 |
| Sanctuary Holistic TherapyTakoma Park | 5 | 8 | — |
| Ketamine Health & RestorationLaurel | 5 | 8 | (301) 298-8267 |
| Adler KetamineAnnapolis | 5 | 1 | (443) 342-3611 |
Ratings come from public Google reviews and change over time. Listing order is not a medical recommendation.
Many patients travel a short distance for a clinic that fits their needs. Explore ketamine care in these nearby communities.
Browsing a wider area? See every clinic in Prince George's County
Conditions Ketamine treats, county-wide options and guides written for Maryland patients.